In this paper, I motivate the view that quantitative parsimony is a theoretical virtue: that is, we should be concerned not only to minimize the number of kinds of entities postulated by our theories (i. e. maximize qualitative parsimony), but we should also minimize the number of entities postulated which fall under those kinds. In order to motivate this view, I consider two cases from the history of science: the postulation of the neutrino and the proposal of Avogadro's hypothesis. I (...) also consider two issues concerning how a principle of quantitative parsimony should be framed. (shrink)

In times of crisis, when current theories are revealed as inadequate to task, and new physics is thought to be required—physics turns to re-evaluate its principles, and to seek new ones. This paper explores the various types, and roles of principles that feature in the problem of quantum gravity as a current crisis in physics. I illustrate the diversity of the principles being appealed to, and show that principles serve in a variety of roles in all stages of the crisis, (...) including in motivating the need for a new theory, and defining what this theory should be like. In particular, I consider: the generalised correspondence principle, UV-completion, background independence, and the holographic principle. I also explore how the current crisis fits with Friedman’s view on the roles of principles in revolutionary theory-change, finding that while many key aspects of this view are not represented in quantum gravity, the view could potentially offer a useful diagnostic, and prescriptive strategy. This paper is intended to be relatively non-technical, and to bring some of the philosophical issues from the search for quantum gravity to a more general philosophical audience interested in the roles of principles in scientific theory-change. (shrink)

A lot of good philosophy is done in the armchair, but is nevertheless a posteriori. This paper clarifies and then defends that claim. Among the a posteriori activities done in the armchair are assembling and evaluating commonplaces; formulating theoretical alternatives; and integrating well-known past a posteriori discoveries. The activity that receives the most discussion, however, is the application of theoretical virtues to choose philosophical theories: the paper argues that much of this is properly seen as a posteriori.

Identification of non-coding RNAs (ncRNAs) has been significantly enhanced due to the rapid advancement in sequencing technologies. On the other hand, semantic annotation of ncRNA data lag behind their identification, and there is a great need to effectively integrate discovery from relevant communities. To this end, the Non-Coding RNA Ontology (NCRO) is being developed to provide a precisely defined ncRNA controlled vocabulary, which can fill a specific and highly needed niche in unification of ncRNA biology.

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 43.1 (2005) 55-81 [Access article in PDF] Self-Knowledge in Descartes and Malebranche Lawrence Nolan John Whipple 1. Introduction Descartes's notorious claim that mind is better known than body has been the target of repeated criticisms, but none appears more challenging than that of his intellectual heir Nicolas Malebranche.1 Whereas other critics—especially twentieth-century philosophers eager to use Descartes as their whipping boy—have often (...) been uncharitable, Malebranche accepts many of the fundamental Cartesian doctrines, including mind-body dualism. But he argues that Descartes's position on knowledge of the mind is internally inconsistent. Malebranche agrees with Descartes that the existence of the mind is better known than that of body, but he vehemently denies that the nature of the mind is better known. This denial is based on his view that we lack a clear idea of the mind.2 [End Page 55]Malebranche's polemic has attracted much attention in recent scholarship.3 The growing consensus among commentators is that Malebranche develops a devastating internal critique of Descartes's theory of the mind. For example, Nicholas Jolley writes: "In his case for his negative thesis [concerning knowledge of the mind] Malebranche mounted a powerful, even annihilating, critique of Descartes. This critique embodies the remarkable insight that there is a serious muddle at the heart of Descartes's whole theory of knowledge."4 In a book-length defense of Malebranche's critique, Tad Schmaltz also emphasizes its internal character: "the interpretation here of Malebranche's theory presents it as fundamentally Cartesian, and thereby serves to reinforce his own view that he has provided an authoritative interpretation of the account of mind in the writings of Descartes and other Cartesians."5 Schmaltz also asserts: "Malebranche took his negative thesis concerning our knowledge of the soul to involve not so much a rejection of Cartesianism as an internal correction of it."6We think such remarks misstate the case. Indeed, we argue in this paper that Malebranche's polemic fails as an internal critique of Descartes's theory of the mind. Although we do not here aspire to defend Descartes's strong thesis—that mind is better known than body—we do think he can consistently maintain that we have a clear and distinct idea of the mind, and thus that our knowledge of the mind's nature is at least on a par with our knowledge of corporeal nature.7 While Malebranche's rhetoric would encourage us to think that the debate between him and his predecessor is being fought on common or neutral ground, the fact is that Malebranche often appeals to assumptions and aspects of his own theory of "Vision in God" that Descartes would reject. Once more, he interprets Descartes's theory of knowledge in ways that are misguided and sometimes even uncharitable. If Malebranche's critique succeeds at all, it succeeds only against a straw man—Malebranche's Descartes and not the historical figure.Ours is not the first effort to defend Descartes against this particular attack. When Malebranche first published his critique in Book Three of his first great work, The Search After Truth (1674),8 Descartes had been dead for over two decades, [End Page 56] but he was ably defended by the famous Cartesian Antoine Arnauld in On True and False Ideas (1683). In the ensuing debate Arnauld was clearly the superior dialectician, but while winning several tactical points, he appears not to fully appreciate the crux of Malebranche's argument, or at least that is the view of Jolley and Schmaltz.9 We have a somewhat higher opinion of Arnauld's side of the debate. Granted, some of his defenses are facile and can be easily dismissed; others however are quite compelling when properly developed. In at least one instance, we attempt to provide that development. At the same time we think it is a mistake to treat Arnauld as Descartes's surrogate or as if he had issued the final salvo from the camp of the orthodox Cartesians. Arnauld was a... (shrink)

A lot of philosophers engage in debates about what claims are “metaphysically necessary”, and a lot more assume with little argument that some classes of claims have the status of “metaphysical necessity”. I think we can usefully replace questions about metaphysical necessity with five other questions which each capture some of what people may have had in mind when talking about metaphysical necessity. This paper explains these five other questions, and then discusses the question “how much of metaphysics is metaphysically (...) necessary?”, and each of its five replacements. (shrink)

There’s an argument around from so-called “linguistic theories of vagueness”, plus some relatively uncontroversial considerations, to powerful metaphysical conclusions. David Lewis employs this argument to support the mereological principle of unrestricted composition, and Theodore Sider employs a similar argument not just for unrestricted composition but also for the doctrine of temporal parts. This sort of argument could be generalised, to produce a lot of other less palatable metaphysical conclusions. However, arguments to Lewis’s and Sider’s conclusions on the basis of considerations (...) about vagueness are uncompelling, even if we accept the crucial premises about vagueness. And a good thing too, since the generalised form of the argument would prove far too much. (shrink)

The Protein Ontology (PRO; http://proconsortium.org) formally defines protein entities and explicitly represents their major forms and interrelations. Protein entities represented in PRO corresponding to single amino acid chains are categorized by level of specificity into family, gene, sequence and modification metaclasses, and there is a separate metaclass for protein complexes. All metaclasses also have organism-specific derivatives. PRO complements established sequence databases such as UniProtKB, and interoperates with other biomedical and biological ontologies such as the Gene Ontology (GO). PRO relates to (...) UniProtKB in that PRO’s organism-specific classes of proteins encoded by a specific gene correspond to entities documented in UniProtKB entries. PRO relates to the GO in that PRO’s representations of organism-specific protein complexes are subclasses of the organism-agnostic protein complex terms in the GO Cellular Component Ontology. The past few years have seen growth and changes to the PRO, as well as new points of access to the data and new applications of PRO in immunology and proteomics. Here we describe some of these developments. (shrink)

In the Fifth Meditation, Descartes makes a remarkable claim about the ontological status of geometrical figures. He asserts that an object such as a triangle has a 'true and immutable nature' that does not depend on the mind, yet has being even if there are no triangles existing in the world. This statement has led many commentators to assume that Descartes is a Platonist regarding essences and in the philosophy of mathematics. One problem with this seemingly natural reading is that (...) it contradicts the conceptualist account of universals that one finds in the Principles of Philosophy and elsewhere. In this paper, I offer a novel interpretation of the notion of a true and immutable nature which reconciles the Fifth Meditation with the conceptualism of Descartes' other work. Specifically, I argue that Descartes takes natures to be innate ideas considered in terms of their so-called 'objective being'. (shrink)

In recent years, sequencing technologies have enabled the identification of a wide range of non-coding RNAs (ncRNAs). Unfortunately, annotation and integration of ncRNA data has lagged behind their identification. Given the large quantity of information being obtained in this area, there emerges an urgent need to integrate what is being discovered by a broad range of relevant communities. To this end, the Non-Coding RNA Ontology (NCRO) is being developed to provide a systematically structured and precisely defined controlled vocabulary for the (...) domain of ncRNAs, thereby facilitating the discovery, curation, analysis, exchange, and reasoning of data about structures of ncRNAs, their molecular and cellular functions, and their impacts upon phenotypes. The goal of NCRO is to serve as a common resource for annotations of diverse research in a way that will significantly enhance integrative and comparative analysis of the myriad resources currently housed in disparate sources. It is our belief that the NCRO ontology can perform an important role in the comprehensive unification of ncRNA biology and, indeed, fill a critical gap in both the Open Biological and Biomedical Ontologies (OBO) Library and the National Center for Biomedical Ontology (NCBO) BioPortal. Our initial focus is on the ontological representation of small regulatory ncRNAs, which we see as the first step in providing a resource for the annotation of data about all forms of ncRNAs. The NCRO ontology is free and open to all users. (shrink)

Unified theories of de se attitudes and de dicto attitudes, along the lines of David Lewis’s proposal, face a problem. Whether or not they are adequate for representing beliefs, they can misrepresent the content of many of our desires, which rank possible outcomes in which the agent with the desire does not exist. These desires are shown to play a role in the rational explanation of action, and recognising them is important in our understanding of ourselves. Lewis’s account of attitudes (...) de dicto and de se is shown to be unsatisfactory, and the lessons learned are applied more broadly. (shrink)

While there are some empirical problems that could suggest the need for a theory of quantum gravity, most of these are not standardly taken as motivations for seeking a new theory. Rather, the quest for a theory of quantum gravity has been primarily motivated, guided, and constrained by philosophical and theoretical concerns. A critical examination of these can help us better understand what the theory is supposed to achieve—and, further, what it should be expected to achieve. On the other hand, (...) there are various approaches towards finding a theory of quantum gravity, with different aims, methods, and starting-points—they disagree on what the theory is supposed to be like. A relevant question is then: what is it that unites these approaches such that we classify them as approaches to quantum gravity? This paper argues that a basic characterisation of the theory can be given in terms of the minimal shared motivation across these different approaches, and that this itself can be seen as motivated by various other problems that have been appealed to as reasons for seeking a theory of quantum gravity. (shrink)

I argue that Graham Priest's story 'Sylvan's Box' has an attractive consistent reading. Priest's hope that this story can be used as an example of a non-trivial 'essentially inconsistent' story is thus threatened. I then make some observations about the role 'Sylvan's Box' might play in a theory of unreliable narrators.

To what extent do true predications correspond to truthmakers in virtue of which those predications are true? One sort of predicate which is often thought to not be susceptible to an ontological treatment is a predicate for instantiation, or some corresponding predication (trope-similarity or set-membership, for example). This paper discusses this question, and argues that an "ontological" approach is possible here too: where this ontological approach goes beyond merely finding a truthmaker for claims about instantiation. Along the way a version (...) of the problem of the regress of instantiation is posed and solved. (shrink)

David Lewis’s arguments against magical ersatzism are notoriously puzzling. Untangling different strands in those arguments is useful for bringing out what he thought was wrong with not just one style of theory about possible worlds, but with much of the contemporary metaphysics of abstract objects. After setting out what I take Lewis’s arguments to be and how best to resist them, I consider the application of those arguments to general theories of properties and relations. The constraints Lewis motivates turn out (...) to yield an argument for concretism about possible individuals that is quite different from the better-known Lewisian arguments for that position. The discussion also touches on the puzzling question of whether things are the way they are because of the properties they have, or are the properties and relations the way they are because of the things that have them. (shrink)

Principles are central to physical reasoning, particularly in the search for a theory of quantum gravity, where novel empirical data are lacking. One principle widely adopted in the search for QG is ultraviolet completion: the idea that a theory should hold up to all possible high energies. We argue— contra standard scientific practice—that UV-completion is poorly motivated as a guiding principle in theory-construction, and cannot be used as a criterion of theory-justification in the search for QG. For this, we explore (...) the reasons for expecting, or desiring, a UV-complete theory, as well as analyse how UV-completion is used, and how it should be used, in various specific approaches to QG. 1Introduction 1.1Principles in theory development and evaluation 2Primer on UV-Completion, Renormalizability, and All That 2.1Renormalizability and UV-completion 2.2Other forms of UV-completion 3Why Should QG Be UV-Complete? 3.1UV-completion and fundamentality 3.2UV-completion and minimal length 4UV-Completion in Different Approaches to QG 4.1String theory 4.2Asymptotic safety 4.3Causal dynamical triangulation 4.4Higher derivative approaches 4.5Supergravity 4.6Causal set theory 4.7Canonical QG 4.8Loop quantum gravity 4.9Approaches based on alternative gravitational theories 4.10Emergent gravity approaches 5UV-Completion as a Guiding Principle in QG 6Conclusion. (shrink)

This introduction to the roles infinity plays in metaphysics includes discussion of the nature of infinity itself; infinite space and time, both in extent and in divisibility; infinite regresses; and a list of some other topics in metaphysics where infinity plays a significant role.

I think that there is an awful lot wrong with the exclusion problem. So, it seems, does just about everybody else. But of course everyone disagrees about exactly _what_ is wrong with it, and I think there is more to be said about that. So I propose to say a few more words about why the exclusion problem is not really a problem after all—at least, not for the nonreductive physicalist. The genuine _dualist_ is still in trouble. Indeed, one of (...) my main points will be that the nonreductive physicalist is in a rather different position vis à vis the exclusion problem than the dualist is. Properly understanding nonreductive physicalism—and clearly recognizing that it is, after all, a form of _physicalism_—goes a long way toward solving the exclusion problem. (shrink)

Part of a book symposium on Graham Priest's Towards Non-Being.

I argue that Descartes intended the so-called ontological "argument" as a self-validating intuition, rather than as a formal proof. The textual evidence for this view is highly compelling, but the strongest support comes from understanding Descartes's diagnosis for why God's existence is not 'immediately' self-evident to everyone and the method of analysis that he develops for making it self-evident. The larger aim of the paper is to use the ontological argument as a case study of Descartes's nonformalist theory of deduction (...) and his method of analysis, showing how he conceives the latter as a form of philosophical therapy. (shrink)

When invited to consider the methodology of contemporary metaphysics, quite a number of procedures spring to mind as part of the metaphysician's toolkit. These include: eliciting and relying on intuitions; solving location problems and using “conceptual analysis”; inference to the best theory, both on internal metaphysical grounds and drawing from the theoretical reaches of the sciences; working on topics clearly close to, or even overlapping, those of other areas of inquiry using techniques of those other areas; achieving coherence with other (...) theories developed with other aims; and employing deductive reasoning to yield surprising conclusions. Many of these techniques are associated with significant and growing literatures about their scope, epistemic justification, suitability to different metaphysical problems, and so on. (shrink)

In seeking an answer to the question of what it means for a theory to be fundamental, it is enlightening to ask why the current best theories of physics are not generally believed to be fundamental. This reveals a set of conditions that a theory of physics must satisfy in order to be considered fundamental. Physics aspires to describe ever deeper levels of reality, which may be without end. Ultimately, at any stage we may not be able to tell whether (...) we've reached rock bottom, or even if there is a base level – nevertheless, I draft a checklist to help us identify when to stop digging, in the case where we may have reached a candidate for a final theory. Given that the list is – according to (current) mainstream belief in high-energy physics – complete, and each criterion well-motivated, I argue that a physical theory that satisfies all the criteria can be assumed to be fundamental in the absence of evidence to the contrary (i.e., I argue that the necessary conditions are jointly sufficient for a claim of fundamentality in physics). (shrink)

The moral problem, as articulated by Smith, arises out of the attempt to introduce the experimental method of reasoning into moral subjects, developed by Hume. This paper returns to Locke’s earlier attempt to provide an empirically adequate account of morality and the debate his attempt generated. It argues that the seeds of a more adequate, naturalistic account of the metaphysics and epistemology of morals than that developed by either Locke or Hume can already be found in aspects of Locke’s Essay (...) and in the defence of his views published by Catharine Trotter Cockburn. Locke and Cockburn find a natural, intrinsically moral, human disposition in our tendency to judge the moral good or evil of persons or actions in the light of their conformity with a moral law. It is constitutive of our nature as social beings that we are endowed ‘with a moral sense or conscience, that approves of virtuous actions, and disapproves the contrary.’ Moral laws are those prohibitions and obligations that benefit others and society as a whole. Thus, the question of natural, moral motivation is seen to be independent of the question of the objective grounds of moral truth. In virtue of our nature as social beings we are motivated to do what is approved of by other members of our society. Whether what is approved of by a society genuinely fosters the welfare of its members is an independent, a posteriori question that can only be answered through reasoned, empirically informed debate. (shrink)

Between 1653 and 1655 Margaret Cavendish makes a radical transition in her theory of matter, rejecting her earlier atomism in favour of an infinitely-extended and infinitely-divisible material plenum, with matter being ubiquitously self-moving, sensing, and rational. It is unclear, however, if Cavendish can actually dispense of atomism. One of her arguments against atomism, for example, depends upon the created world being harmonious and orderly, a premise Cavendish herself repeatedly undermines by noting nature’s many disorders. I argue that her supposed difficulties (...) with atomism expose a deeper tension in her work between two fundamental metaphysical commitments each of which has substantial philosophical support: her monist theory of the material world (which maintains that there exists just one natural substance which is the single principal cause) and her occasional theory of causation (which requires multiple finite principal causes in nature -- causes that might be considered individual substances). Her monism undermines atomism while her theory of occasional cause seems to rest on a conception of nature that would be especially friendly to atomism. I argue further that we can solve this tension within a Cavendishian framework in such a way as to preserve her theory of causation and her monism, but that this solution depends upon our taking her monism in a particular (and weak) form. I finally note that we can best make sense of her unique and interesting form of monism by acknowledging her social-political motivations in addition to her motivations in natural philosophy. (shrink)

Singularities in general relativity and quantum field theory are often taken not only to motivate the search for a more-fundamental theory (quantum gravity, QG), but also to characterise this new theory and shape expectations of what it is to achieve. Here, we first evaluate how particular types of singularities may suggest an incompleteness of current theories. We then classify four different 'attitudes' towards singularities in the search for QG, and show, through examples in the physics literature, that these lead to (...) different scenarios for the new theory. Two of the attitudes prompt singularity resolution, but only one suggests the need for a theory of QG. Rather than evaluate the different attitudes, we close with some suggestions of factors that influence the choice between them. (shrink)

An overview of hyperintensionality is provided. Hyperintensional languages have expressions with meanings that are more fine-grained than necessary equivalence. That is, the expressions may necessarily co-apply and yet be distinct in meaning. Adequately accounting for theories cast in hyperintensional languages is important in the philosophy of language; the philosophy of mind; metaphysics; and elsewhere. This entry presents a number of areas in which hyperintensionality is important; a range of approaches to theorising about hyperintensional matters; and a range of debates that (...) attention to hyperintensional constructions has generated. (shrink)

Lewis is famous as a contemporary philosophical system-builder. The most obvious way his philosophy exhibited a system was in its content: Lewis’s metaphysics, for example, provided answers to many metaphysical puzzles in an integrated way, and there are illuminating connections to be drawn between his general metaphysical views and, for example, his various views about the mind and its place in nature.

I take up reflections on my book, On Manners, by Professors Van Norden, Cline, and Olberding. In response to Professor Van Norden, I further explain and defend my employment of Kant, arguing that Kantianism offers distinctive and valuable resources for thinking about manners. I suggest similarities between Kant and Xunzi 荀子. In response to Professor Cline, I take up the question of the developmental function of manners and explore in further detail the ways in which our social roles both give (...) us standing to perform certain ritual actions and also make demands on us about whether and how we perform them. In response to Professor Olberding, I revisit one of the themes from the book, virtuous hospitality. I argue that we may have moral reason to adapt ourselves and our practices to certain aesthetic standards for domestic activities, rather than adjust the standards to suit our individual tastes. (shrink)

Curry's paradox for "if.. then.." concerns the paradoxical features of sentences of the form "If this very sentence is true, then 2+2=5". Standard inference principles lead us to the conclusion that such conditionals have true consequents: so, for example, 2+2=5 after all. There has been a lot of technical work done on formal options for blocking Curry paradoxes while only compromising a little on the various central principles of logic and meaning that are under threat. -/- Once we have a (...) sense of the technical options, though, a philosophical choice remains. When dealing with puzzles in the logic of conditionals, a natural place to turn is independently motivated semantic theories of the behaviour of "if... then...". This paper argues that the closest-worlds approach outlined in Nolan 1997 offers a philosophically satisfying reason to deny conditional proof and so block the paradoxical Curry reasoning, and can give the verdict that standard Curry conditionals are false, along with related "contraction conditionals". (shrink)

This paper builds on the system of David Lewis’s “Parts of Classes” to provide a foundation for mathematics that arguably requires not only no distinctively mathematical ideological commitments (in the sense of Quine), but also no distinctively mathematical ontological commitments. Provided only that there are enough individual atoms, the devices of plural quantification and mereology can be employed to simulate quantification over classes, while at the same time allowing all of the atoms (and most of their fusions with which we (...) are concerned) to be individuals (that is, urelements of classes). The final section of the paper canvasses some reasons to be committed to the required ontology for other than mathematical reasons. (shrink)

This paper explores a special kind of loop of grounding: cosmic loops. A cosmic loop is a loop that intuitively requires us to go "around" the entire universe to come back to the original ground. After describing several kinds of cosmic loop scenarios, I will discuss what we can learn from these scenarios about constraints on grounding; the conceivability of cosmic loops; the possibility of cosmic loops; and the prospects for salvaging local reflexivity, asymmetry and transitivity of grounding in a (...) world containing a cosmic loop of ground. The considerations raised in this paper also bear on what we should think about relations that are meant to support grounding relations: in particular, revisions to theories of the part-whole relation are discussed. (shrink)

Marriages come in a very wide variety: if the reports of anthropologists and historians are to be believed, an extraordinarily wide variety. This includes some of the more unusual forms, including marriage to the dead; to the gods; and even to plants. This does suggest that few proposed marriage relationships would require 'redefining marriage': but on the other hand, it makes giving a general theory of marriage challenging. So one issue we should face is how accepting we should be of (...) the reports: to what extent reported 'marriages' really are marriages. This paper defends the view that almost all of these reported marriages are in fact marriages, and suggests some theoretical approaches that may be generous enough to account for this. (shrink)

Many people are inclined to think that consequences of actions, or perhaps reasonably expected consequences of those actions, have moral weight. Firing off shotguns in crowded areas is typically wrong, at least in part, because of the people who get maimed and killed. Committed consequentialists think that consequences (either actual consequences, or expected consequences, or intended consequences, or reasonably expected consequences, or maybe some other different shade) are all that matters, morally speaking. Lying and stealing are wrong, when they are (...) wrong, only because of the consequences they have – these may include direct consequences, such as the loss of property by another, or another’s hurt at being deceived, but also indirect consequences, such as setting a bad example or cultivating a disposition to lie or steal too easily that risks manifesting when the direct harm would be more serious. Consequentialists do not have to agree on much else – they may not agree what the morally relevant consequences are (Bentham thought they were a matter of pleasure and avoidance of pain, others may define a conception of human welfare, or preference satisfaction, or something else), they may disagree over whether there is one sort of consequence or many sorts that are relevant, and they can disagree about how the consequences matter. A maximiser thinks that as much as possible of the relevant consequences is morally important, others may think that beyond some point, consequences are indifferent, others may think that the average distribution of consequences across agents is what matters, or largely what matters, and so on.1.. (shrink)

Feelings of gratitude toward the natural environment are problematic because gratitude seems to be an appropriate response to someone’s intentional decision to benefit us, and ecosystems that sustain human life do not choose to do so. In accordance with one defense of the rationality and appropriateness of gratitude toward nature, intentional action can be regarded as not being a necessary condition for feelings of gratitude. Instead, gratitude toward an entity can be considered both rational and appropriate when (1) that entity (...) is the source of a valuable and unearned benefit and (2) the benefit did not result from some accidental and/or regrettable feature of that entity’s character. According to this analysis, we can provide a rational ground for gratitude to particular ecosystems by citing the valuable and unearned benefits that we receive from those systems and by demonstrating that these benefits result from elements within the ecosystems that are neither regrettable nor accidental. (shrink)

1. Biomedical sciences are fast-growing fields with unprecedented speed of research outputs, especially in the quantities of papers. Philosophers aiming to study ongoing biomedical changes face cha...

In this paper I describe and defend an account of virtuous motivation that differs from what we might call ordinary moral motivation. It is possible to be morally motivated without being virtuously motivated. In the first half of the essay, I explore different senses of moral motivation and the philosophical puzzles and problems it poses. In the second half, I give an account of virtuous motivation that, unlike ordinary moral motivation, requires the motivational structure characteristic of a fully virtuous person. (...) I draw on Aristotle's account of virtuous action to argue that a fully virtuous agent's judgment reflects a robust form of moral knowledge about what features of an action render it virtuous and hence, choiceworthy. Virtuously motivated actions are chosen in light of those features and are accompanied by the affective state appropriate to the overall moral landscape in which the judgment is made. (shrink)

The philosophy of necessity and possibility has flourished in the last half-century, but much less attention has been paid to the question of how we know what can be the case and what must be the case. Many friends of modal metaphysics and many enemies of modal metaphysics have agreed that while empirical discoveries can tell us what is the case, they cannot shed much light on what must be the case or on what non-actual possibilities there are. In this (...) paper, in contrast, I discuss and defend naturalistic approaches to discovering the facts about necessity and possibility. After some remarks about what methodological naturalism in philosophy might amount to, I argue that naturalistic method in modal investigations may not need to be particularly revisionary of much of what is currently being done in modal investigation. I then discuss a number of respects in which a naturalistic orientation in modal investigation may improve on our current epistemic situation. (shrink)

This paper examines both creepiness and the distinctive reaction had to creepiness, being “creeped out.” The paper defends a response-dependent account of creepiness in terms of this distinctive reaction, contrasting our preferred account to others that might be offered. The paper concludes with a discussion of the value of detecting creepiness.

A standing challenge in the theory of counterfactuals is to solve the “deviation problem”. Consider ordinary counterfactuals involving an antecedent concerning a difference from the actual course of events at a particular time, and a consequent concerning, at least in part, what happens at a later time. In the possible worlds framework, the problem is often put in terms of which are the relevant antecedent worlds. Desiderata for the solution include that the relevant antecedent worlds be governed by the actual (...) laws of nature with no miracles; that the past in those worlds before the antecedent time matches the actual past; that the account is compatible with determinism, and that many of our ordinary counterfactual judgments are correct, and would be correct even given determinism. Many theorists have compromised on one or more of these desiderata, but this paper presents an account employing impossible worlds that satisfies them all. (shrink)

Relationships between current theories, and relationships between current theories and the sought theory of quantum gravity (QG), play an essential role in motivating the need for QG, aiding the search for QG, and defining what would count as QG. Correspondence is the broad class of inter-theory relationships intended to demonstrate the necessary compatibility of two theories whose domains of validity overlap, in the overlap regions. The variety of roles that correspondence plays in the search for QG are illustrated, using examples (...) from specific QG approaches. Reduction is argued to be a special case of correspondence, and to form part of the definition of QG. Finally, the appropriate account of emergence in the context of QG is presented, and compared to conceptions of emergence in the broader philosophy literature. It is argued that, while emergence is likely to hold between QG and general relativity, emergence is not part of the definition of QG, and nor can it serve usefully in the development and justification of the new theory. (shrink)

According to Margaret Cavendish the entire natural world is essentially rational such that everything thinks in some way or another. In this paper, I examine why Cavendish would believe that the natural world is ubiquitously rational, arguing against the usual account, which holds that she does so in order to account for the orderly production of very complex phenomena (e.g. living beings) given the limits of the mechanical philosophy. Rather, I argue, she attributes ubiquitous rationality to the natural world in (...) order to ground a theory of the ubiquitous freedom of nature, which in turn accounts for both the world's orderly and disorderly behavior. (shrink)

One increasingly popular technique in philosophy might be called the "platitudes analysis": a set of widely accepted claims about a given subject matter are collected, adjustments are made to the body of claims, and this is taken to specify a “role” for the phenomenon in question. (Perhaps the best-known example is analytic functionalism about mental states, where platitudes about belief, desire, intention etc. are together taken to give us a "role" for states to fill if they are to count as (...) mental states.) We then look to our best theory of the world to see where this role is satisfied, if at all. Unfortunately, the platitudes analysis, so characterised, does not seem to help when we are doing fundamental metaphysics—when we want to know what, at base, our world is like (and not merely where things like e.g. the mental would be found in an already-specified ontology). Nevertheless, I will argue that the platitudes analysis, properly understood, does have the materials to help us answer questions in fundamental metaphysics as well. I will explore three different ways it can do so. (shrink)

One of the standard approaches to the metaphysics of personal identity has some counter-intuitive ethical consequences when combined with maximising consequentialism and a plausible doctrine about aggregation of consequences. This metaphysical doctrine is the so-called ‘multiple occupancy’ approach to puzzles about fission and fusion. It gives rise to a new version of the ‘utility monster’ problem, particularly difficult problems about infinite utility, and a new version of a Parfit-style ‘repugnant conclusion’. While the article focuses on maximising consequentialism for simplicity, the (...) problems demonstrated apply more widely to a range of ethical views, especially flavours of consequentialism. This article demonstrates how these problems arise, and discusses a number of options available in the light of these problems for a consequentialist tempted by a multiple occupancy metaphysics. (shrink)

Creationism about fictional entities requires a principle connecting what fictions say exist with which fictional entities really exist. The most natural way of spelling out such a principle yields inconsistent verdicts about how many fictional entities are generated by certain inconsistent fictions. Avoiding inconsistency without compromising the attractions of creationism will not be easy.

Research has indicated that microRNAs (miRNAs), a special class of non-coding RNAs (ncRNAs), can perform important roles in different biological and pathological processes. miRNAs’ functions are realized by regulating their respective target genes (targets). It is thus critical to identify and analyze miRNA-target interactions for a better understanding and delineation of miRNAs’ functions. However, conventional knowledge discovery and acquisition methods have many limitations. Fortunately, semantic technologies that are based on domain ontologies can render great assistance in this regard. In our (...) previous investigations, we developed a miRNA domain-specific application ontology, Ontology for MIcroRNA Target (OMIT), to provide the community with common data elements and data exchange standards in the miRNA research. This paper describes (1) our continuing efforts in the OMIT ontology development and (2) the application of the OMIT to enable a semantic approach for knowledge capture of miRNA-target interactions. (shrink)

A pressing problem for many non-realist1 theories concerning various specific subject matters is the challenge of making sense of our ordinary propositional attitude claims related to the subject in question. Famously in the case of ethics, to take one example, we have in ordinary language prima facie ascriptions of beliefs and desires involving moral properties and relationships. In the case, for instance, of “Jason believes that Kylie is virtuous”, we appear to have a belief which takes Kylie to be a (...) certain way. If Jason desires that Kylie acts as she ought, he appears to have a desire which has as its content that Kylie perform actions of a certain sort (i.e. the actions that she ought to perform). However, for non-cognitivists in ethics who reject the idea that sentences such as “Kylie is virtuous” or “Kylie acts as she ought” are in the business of making truth-apt claims, or representing that certain moral features are possessed by objects or events, or even, in extreme cases, that such claims express propositions at all, the semantic analysis of the example propositional attitude claims made about Jason will have to be non-standard. (This is merely an application of the well-known “Frege-Geach problem” (see Geach 1965) to the case of embedding moral vocabulary in propositional-attitude ascriptions.). (shrink)

This paper discusses an infinite regress that looms behind a certain kind of historical explanation. The movement of one barbarian group is often explained by the movement of others, but those movements in turn call for an explanation. While their explanation can again be the movement of yet another group of barbarians, if this sort of explanation does not stop somewhere we are left with an infinite regress of barbarians. While that regress would be vicious, it cannot be accommodated by (...) several general views about what viciousness in infinite regresses amounts to. This example is additional evidence that we should prefer a pluralist approach to infinite regresses. (shrink)

The question of what truths are necessary in the broadest possible sense is a difficult one to answer, as is the question of what the limits are to what is possible. (Most people would see these two questions as different sides of the same coin, of course, since many think the question of what is possible is just the question of what is not necessarily ruled out). We have three general sorts of strategies for determining whether something is necessary (or (...) possible). We can identify it in a class that we were previously sure was a class of things that are necessary – we might show it is a theorem of a logical system that we have confidence in, or that the sentence appears to be true simply in virtue of the meanings of the words, or that it is a true statement involving names or about natural kinds of the “necessary a posteriori” sort discussed by Kripke and Putnam, and there are perhaps other classes of claims which we are prepared to accept are necessary if true.1 Likewise, we might establish the possibility of something occurring by reference to a class of well-established or uncontroversial possibilities: e.g. we are inclined to think that it is possible (in the broadest sense) for an event to occur in the future if one of the same kind has occurred in the past. (shrink)

Readers of fictions sometimes resist taking certain kinds of claims to be true according to those fictions, even when they appear explicitly or follow from applying ordinary principles of interpretation. This "imaginative resistance" is often taken to be significant for a range of philosophical projects outside aesthetics, including giving us evidence about what is possible and what is impossible, as well as the limits of conceivability, or readers' normative commitments. I will argue that this phenomenon cannot do the theoretical work (...) that has been asked of it. Resistance to taking things to be fictional is often best explained by unfamiliarity with kinds of fictions than any representational, normative, or cognitive limits. With training and experience, any understandable proposition can be made fictional and be taken to be fictional by readers. This requires a new understanding both of imaginative resistance, and what it might be able to tell us about topics like conceivability or the bounds of possibility. (shrink)